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Article Dans Une Revue European Journal of Applied Physiology Année : 2016

Individuality of breathing during volitional moderate hyperventilation

Résumé

Purpose: The aim of this study is to investigate the individ- uality of airflow shapes during volitional hyperventilation. Methods: Ventilation was recorded on 18 healthy sub- jects following two protocols: (1) spontaneous breath- ing (SP1) followed by a volitional hyperventilation at each subject’s spontaneous (HVSP) breathing rate, (2) spontaneous breathing (SP2) followed by hyperventila- tion at 20/min (HV20). HVSP and HV20 were performed at the same level of hypocapnia: end tidal CO2 (FETCO2) was maintained at 1 % below the spontaneous level. At each breath, the tidal volume (VT), the breath (TTOT), the inspiratory (TI) and expiratory durations, the minute ven- tilation, VT/TI, TI/TTOT and the airflow shape were quan- tified by harmonic analysis. Under different conditions of breathing, we test if the airflow profiles of the same individual are more similar than airflow profiles between individuals. Results: Minute ventilation was not signifi- cantly different between SP1 (6.71 ± 1.64 l·min−1) and SP2 (6.57 ± 1.31 l·min−1) nor between HVSP (15.88 ± 4.92 l·min−1) and HV20 (15.87 ± 4.16 l·min−1). Similar results were obtained for FETCO2 between SP1 (5.06 ± 0.54 %) and SP2 (5.00 ± 0.51 %), and HVSP (4.07 ± 0.51 %) and HV20 (3.88 ± 0.42 %). Only TI/TTOT remained unchanged in all four conditions. Airflow shapes were similar when comparing SP1-SP2, HVSP-HV20, and SP1-HVSP but not similar when comparing SP2-HV20. Conclusions: These results suggest the existence of an individuality of airflow shape during volitional hyperven- tilation. We conclude that volitional ventilation alike auto- matic breathing follows inherent properties of the ventila- tory system. Registered by Pascale Calabrese on ClinicalTrials.gov, # NCT01881945.
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Dates et versions

hal-02075476 , version 1 (05-08-2019)

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Tudor Besleaga, Michael Blum, Raphael Briot, Victor Vovc, Ion Moldovanu, et al.. Individuality of breathing during volitional moderate hyperventilation. European Journal of Applied Physiology, 2016, 116 (1), pp.217-225. ⟨10.1007/s00421-015-3260-3⟩. ⟨hal-02075476⟩
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