Meningococcal strain evolution, dusty dry air and respiratory tract infections: An explosive relationship
Résumé
In this article of EBioMedicine, Topaz and colleagues [1] present a phylogenetic overview with more than 700 meningococcal strains isolated since the introduction of a serogroup A-specific conjugate vaccine (MenAfriVac®) in the meningitis belt. This vaccination has led to quasi-elimination of serogroup A disease, which used to be the predominant burden, but the emergence of a new serogroup C strain during the vaccination roll-out substantially reduced the net benefit for the region.
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