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Journal Articles Macromolecular Bioscience Year : 2016

Cellularized Cellular Solids via Freeze-Casting

Abstract

The elaboration of metabolically active cell-containing materials is a decisive step toward the successful application of cell based technologies. The present work unveils a new process allowing to simultaneously encapsulate living cells and shaping cell-containing materials into solid-state macroporous foams with precisely controlled morphology. Our strategy is based on freeze casting, an ice templating materials processing technique that has recently emerged for the structuration of colloids into macroporous materials. Our results indicate that it is possible to combine the precise structuration of the materials with cellular metabolic activity for the model organism Saccharomyces cerevisiae.

Dates and versions

hal-01286119 , version 1 (10-03-2016)

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Sarah Christoph, Julien Kwiatoszynski, Thibaud Coradin, Francisco M. Fernandes. Cellularized Cellular Solids via Freeze-Casting. Macromolecular Bioscience, 2016, 16 (2), pp.182-187. ⟨10.1002/mabi.201500319⟩. ⟨hal-01286119⟩
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