The EHA Research Roadmap: Normal Hematopoiesis
Thierry Jaffredo
(1)
,
Alessandra Balduini
(2)
,
Anna Bigas
(3, 4, 5)
,
Rosa Bernardi
(6)
,
Dominique Bonnet
(7)
,
Bruno Canque
(8, 9)
,
Pierre Charbord
(1)
,
Anna Cumano
(10)
,
Ruud Delwel
(11)
,
Charles Durand
(1)
,
Willem Fibbe
(12)
,
Lesley Forrester
(13)
,
Lucia de Franceschi
(14)
,
Cedric Ghevaert
(15)
,
Bjørn Gjertsen
(16, 17)
,
Berthold Gottgens
(15)
,
Thomas Graf
(18, 19)
,
Olaf Heidenreich
(20)
,
Olivier Hermine
(21, 22)
,
Douglas Higgs
(23)
,
Marina Kleanthous
(24)
,
Hannes Klump
(25)
,
Valerie Kouskoff
(26)
,
Daniela Krause
(27, 28)
,
George Lacaud
(26)
,
Cristina Lo Celso
(29)
,
Joost H.A. Martens
(30)
,
Simón Méndez-Ferrer
(15, 31)
,
Pablo Menendez
(5, 4, 32, 33)
,
Robert Oostendorp
(34)
,
Sjaak Philipsen
(11)
,
Bo Porse
(35)
,
Marc Raaijmakers
(11)
,
Catherine Robin
(36, 37)
,
Henk Stunnenberg
(20)
,
Kim Theilgaard-Mönch
(35)
,
Ivo Touw
(11)
,
William Vainchenker
(38, 39)
,
Joan-Lluis Vives Corrons
(4)
,
Laurent Yvernogeau
(1)
,
Jan Jacob Schuringa
(40)
1
LBD -
Laboratoire de Biologie du Développement [IBPS]
2 UNIPV - Università degli Studi di Pavia [Italia] = University of Pavia [Italy] = Université de Pavie [Italie]
3 IMIM-Hospital del Mar
4 IJC - Josep Carreras Leukaemia Research Institute
5 ISCIII - Instituto de Salud Carlos III [Madrid]
6 IRCCS San Raffaele Scientific Institute [Milan, Italie]
7 The Francis Crick Institute [London]
8 HIPI (UMR_S_976 / U976) - Immunologie humaine, physiopathologie & immunothérapie
9 IRSL - Institut de Recherche Saint-Louis - Hématologie Immunologie Oncologie (Département de recherche de l’UFR de médecine ; ex- Institut Universitaire Hématologie-IUH)
10 Lymphopoïèse (UMR_1223 / U1223 / U-Pasteur_4) - Lymphopoïèse
11 Erasmus MC - Erasmus University Medical Center [Rotterdam]
12 LUMC - Leiden University Medical Center
13 Edin. - University of Edinburgh
14 UNIVR - Università degli studi di Verona = University of Verona
15 CAM - University of Cambridge [UK]
16 Haukeland University Hospital
17 UiB - University of Bergen
18 BIST - Barcelona Institute of Science and Technology
19 UPF - Universitat Pompeu Fabra [Barcelona]
20 Princess Máxima Center for Pediatric Oncology [Utrecht, Netherlands]
21 Imagine - U1163 - Imagine - Institut des maladies génétiques (IHU)
22 Hôpital Necker - Enfants Malades [AP-HP]
23 John Radcliffe Hospital [Oxford University Hospital]
24 Cyprus Institute of Neurology and Genetics
25 Uniklinik Essen - Universitätsklinikum Essen [Universität Duisburg-Essen]
26 University of Manchester [Manchester]
27 Goethe-Universität Frankfurt am Main
28 Georg-Speyer-Haus
29 Imperial College London
30 Radboud University [Nijmegen]
31 NHSBT
32 UB - Universitat de Barcelona
33 ICREA - Institució Catalana de Recerca i Estudis Avançats = Catalan Institution for Research and Advanced Studies
34 TUM - Technische Universität Munchen - Technical University Munich - Université Technique de Munich
35 UCPH - University of Copenhagen = Københavns Universitet
36 Hubrecht Institute [Utrecht, Netherlands]
37 UMCU - University Medical Center [Utrecht]
38 IGR - Institut Gustave Roussy
39 Dynamo - Dynamique moléculaire de la transformation hématopoïétique
40 UMCG - University Medical Center Groningen [Groningen]
2 UNIPV - Università degli Studi di Pavia [Italia] = University of Pavia [Italy] = Université de Pavie [Italie]
3 IMIM-Hospital del Mar
4 IJC - Josep Carreras Leukaemia Research Institute
5 ISCIII - Instituto de Salud Carlos III [Madrid]
6 IRCCS San Raffaele Scientific Institute [Milan, Italie]
7 The Francis Crick Institute [London]
8 HIPI (UMR_S_976 / U976) - Immunologie humaine, physiopathologie & immunothérapie
9 IRSL - Institut de Recherche Saint-Louis - Hématologie Immunologie Oncologie (Département de recherche de l’UFR de médecine ; ex- Institut Universitaire Hématologie-IUH)
10 Lymphopoïèse (UMR_1223 / U1223 / U-Pasteur_4) - Lymphopoïèse
11 Erasmus MC - Erasmus University Medical Center [Rotterdam]
12 LUMC - Leiden University Medical Center
13 Edin. - University of Edinburgh
14 UNIVR - Università degli studi di Verona = University of Verona
15 CAM - University of Cambridge [UK]
16 Haukeland University Hospital
17 UiB - University of Bergen
18 BIST - Barcelona Institute of Science and Technology
19 UPF - Universitat Pompeu Fabra [Barcelona]
20 Princess Máxima Center for Pediatric Oncology [Utrecht, Netherlands]
21 Imagine - U1163 - Imagine - Institut des maladies génétiques (IHU)
22 Hôpital Necker - Enfants Malades [AP-HP]
23 John Radcliffe Hospital [Oxford University Hospital]
24 Cyprus Institute of Neurology and Genetics
25 Uniklinik Essen - Universitätsklinikum Essen [Universität Duisburg-Essen]
26 University of Manchester [Manchester]
27 Goethe-Universität Frankfurt am Main
28 Georg-Speyer-Haus
29 Imperial College London
30 Radboud University [Nijmegen]
31 NHSBT
32 UB - Universitat de Barcelona
33 ICREA - Institució Catalana de Recerca i Estudis Avançats = Catalan Institution for Research and Advanced Studies
34 TUM - Technische Universität Munchen - Technical University Munich - Université Technique de Munich
35 UCPH - University of Copenhagen = Københavns Universitet
36 Hubrecht Institute [Utrecht, Netherlands]
37 UMCU - University Medical Center [Utrecht]
38 IGR - Institut Gustave Roussy
39 Dynamo - Dynamique moléculaire de la transformation hématopoïétique
40 UMCG - University Medical Center Groningen [Groningen]
Thierry Jaffredo
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Anna Bigas
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Dominique Bonnet
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Olivier Hermine
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William Vainchenker
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Jan Jacob Schuringa
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Résumé
In 2016, the European Hematology Association (EHA) published the EHA Roadmap for European Hematology Research1 aiming to highlight achievements in the diagnostics and treatment of blood disorders, and to better inform European policy makers and other stakeholders about the urgent clinical and scientific needs and priorities in the field of hematology. Each section was coordinated by 1–2 section editors who were leading international experts in the field. In the 5 years that have followed, advances in the field of hematology have been plentiful. As such, EHA is pleased to present an updated Research Roadmap, now including 11 sections, each of which will be published separately. The updated EHA Research Roadmap identifies the most urgent priorities in hematology research and clinical science, therefore supporting a more informed, focused, and ideally a more funded future for European hematology research. The 11 EHA Research Roadmap sections include Normal Hematopoiesis; Malignant Lymphoid Diseases; Malignant Myeloid Diseases; Anemias and Related Diseases; Platelet Disorders; Blood Coagulation and Hemostatic Disorders; Transfusion Medicine; Infections in Hematology; Hematopoietic Stem Cell Transplantation; CAR-T and Other Cell-based Immune Therapies; and Gene Therapy.
Domaines
Biologie cellulaire
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The_EHA_Research_Roadmap__Normal_Hematopoiesis.11.pdf (879.73 Ko)
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