Emergence and clonal expansion of Vibrio aestuarianus lineages pathogenic for oystersin Europe - Interactions hôtes-pathologies-environnement Accéder directement au contenu
Article Dans Une Revue Molecular Ecology Année : 2023

Emergence and clonal expansion of Vibrio aestuarianus lineages pathogenic for oystersin Europe

Michelle Geary
  • Fonction : Auteur
Alessia Vetri
  • Fonction : Auteur
Ana Roque
  • Fonction : Auteur
Alison Garden
  • Fonction : Auteur

Résumé

Crassostrea gigas oysters represent a significant global food source, with 4.7 million tons harvested per year. In 2001, the bacterium Vibrio aestuarianus francensis emerged as a pathogen that causes adult oyster mortality in France and Ireland. Its impact on oyster aquaculture has increased in Europe since its reemergence in 2012. To better understand the evolutionary mechanisms leading to the emergence and persistence over time of this pathogen, we conducted a survey of mollusk diseases through national reference laboratories (NRLs) across Europe. We analyzed54 new genomes of Vibrio Aestuarianus (Va) isolated from multiple environmental compartments since 2001, in areas with and withoutbivalve mortalities. We used a combination of comparative genomics and population genetics approaches and show thatVa has a classical epidemic population structure from which the pathogenic Va francensis subspecies emerged and clonally expanded. Furthermore, we identified a specific cus-cop-containing island conferring copper resistance to Va francensis whose acquisition may have favored the emergence of pathogenic lineages adapted and specialized to oysters.
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Dates et versions

hal-04013412 , version 1 (03-03-2023)

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Aurélie Mesnil, Maude Jacquot, Céline Garcia, Delphine Tourbiez, Lydie Canier, et al.. Emergence and clonal expansion of Vibrio aestuarianus lineages pathogenic for oystersin Europe. Molecular Ecology, inPress, ⟨10.1111/mec.16910⟩. ⟨hal-04013412⟩
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