This article introduces the MediMoov platform, a software designed for motor rehabilitation, which leverages motion-based interaction methods to combine video gaming with physical therapy exercises (physio-gaming). It’s widely used in various healthcare environments, including rehabilitation centers and retirement homes. Users support its effectiveness, ease of use, simple setup, and diverse exercise options. Despite its success, MediMoov faces challenges, notably its reliance on the Microsoft Kinect v2 sensor. User feedback indicates a need to expand movement range for finer motor skills and enhance motion capture for disabled users. Clinicians desire a motion estimation tool offering biomechanically pertinent data. To address these issues, the article suggests upgrading MediMoov with advanced motion estimation, tracking, and gesture recognition technologies compatible with different sensors, including RGB cameras. These enhancements aim to make the platform more inclusive and effective in rehabilitation through physio-gaming, enlarging its utility and improving user experience for a diverse range of needs.