Optimal Control of Dengue Transmission: A Comparative Study of Vaccination and Treatment Efficacy
Abstract
Evaluating public health intervention techniques is essential to manage dengue successfully. This study proposes an epidemic model that includes two essential therapeutic interventions: vaccination and treating infected individuals to better understand dengue transmission dynamics. We introduce a seven-state model and investigate the model's endemic and disease-free equilibria. Results show that when vaccination efficacy is low, therapy is a more effective strategy for lowering dengue cases, whereas a highly effective vaccine significantly reduces dengue cases. The study also formulates an optimal control problem, suggesting that combined strategies are more effective in mitigating the disease spread.
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