Old and New Challenges in Uveitis Associated with Behçet’s Disease - Immunologie-Immunopathologie-Immunothérapie Accéder directement au contenu
Article Dans Une Revue Journal of Clinical Medicine Année : 2021

Old and New Challenges in Uveitis Associated with Behçet’s Disease

Julie Gueudry
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Mathilde Leclercq
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Bahram Bodaghi
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Résumé

Behçet’s disease (BD) is a systemic vasculitis disease of unknown origin occurring in young people, which can be venous, arterial or both, classically occlusive. Ocular involvement is particularly frequent and severe; vascular occlusion secondary to retinal vasculitis may lead to rapid and severe loss of vision. Biologics have transformed the management of intraocular inflammation. However, the diagnosis of BD is still a major challenge. In the absence of a reliable biological marker, diagnosis is based on clinical diagnostic criteria and may be delayed after the appearance of the onset sign. However, therapeutic management of BD needs to be introduced early in order to control inflammation, to preserve visual function and to limit irreversible structural damage. The aim of this review is to provide current data on how innovations in clinical evaluation, investigations and treatments were able to improve the prognosis of uveitis associated with BD.

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Organes des sens
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Dates et versions

hal-03248621 , version 1 (03-06-2021)

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Julie Gueudry, Mathilde Leclercq, David Saadoun, Bahram Bodaghi. Old and New Challenges in Uveitis Associated with Behçet’s Disease. Journal of Clinical Medicine, 2021, 10 (11), pp.2318. ⟨10.3390/jcm10112318⟩. ⟨hal-03248621⟩
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