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Propagation of Distinct α-Synuclein Strains Within Human Reconstructed Neuronal Network and Associated Neuronal Dysfunctions

Simona Gribaudo , Luc Bousset , Josquin Courte , Ronald Melki , Jean-Michel Peyrin et al.
Protein Aggregation, 2551 (10), Springer US, pp.357-378, 2023, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2597-2_24⟩
Chapitre d'ouvrage hal-03836488v1
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Photoreceptor Cell Replacement Using Pluripotent Stem Cells: Current Knowledge and Remaining Questions

Christelle Monville , Olivier Goureau , Karim Ben M'Barek
Cold Spring Harbor Perspectives in Medicine, 2022
Article dans une revue hal-03932669v1

Myotonic dystrophy RNA toxicity alters morphology, adhesion and migration of mouse and human astrocytes

Diana Dincã , Anchel González-Barriga , Geraldine Sicot , Louison Lallemant , Laure-Elise Pillet et al.
2022
Pré-publication, Document de travail hal-03863376v1

Physiology of PNS axons relies on glycolytic metabolism in myelinating Schwann cells

Marie Deck , Gerben van Hameren , Graham Campbell , Nathalie Bernard-Marissal , Jérôme Devaux et al.
PLoS ONE, 2022, 17 (10), pp.e0272097. ⟨10.1371/journal.pone.0272097⟩
Article dans une revue hal-03861076v1

Severe congenital myasthenic syndromes caused by agrin mutations affecting secretion by motoneurons

Arnaud Jacquier , Valérie Risson , Thomas Simonet , Florine Roussange , Nicolas Lacoste et al.
Acta Neuropathologica, 2022, 144 (4), pp.707-731. ⟨10.1007/s00401-022-02475-8⟩
Article dans une revue hal-03863096v1

RNA helicase-dependent gene looping impacts messenger RNA processing

Sophie Terrone , Jessica Valat , Nicolas Fontrodona , Guillaume Giraud , Jean-Baptiste Claude et al.
Nucleic Acids Research, 2022, 50 (16), pp.9226-9246. ⟨10.1093/nar/gkac717⟩
Article dans une revue hal-03842696v1
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Modélisation des atteintes neurologiques du syndrome de Wolfram de type 1 : exploitation des cellules souches pluripotentes induites et de leurs dérivés

Axel Sciauvaud
Physiologie [q-bio.TO]. Université Paris-Saclay, 2022. Français. ⟨NNT : 2022UPASQ034⟩
Thèse tel-03917165v1
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Human Cytomegalovirus Modifies Placental Small Extracellular Vesicle Composition to Enhance Infection of Fetal Neural Cells In Vitro

Mathilde Bergamelli , Hélène Martin , Yann Aubert , Jean-Michel Mansuy , Marlène Marcellin et al.
Viruses, 2022, 14 (9), pp.2030. ⟨10.3390/v14092030⟩
Article dans une revue hal-03800516v1

Moxifloxacin rescues SMA phenotypes in patient-derived cells and animal model

Camille Januel , Giovanna Menduti , Kamel Mamchaoui , Cecile Martinat , Ruben Artero et al.
Cellular and Molecular Life Sciences, 2022, 79 (8), pp.441. ⟨10.1007/s00018-022-04450-8⟩
Article dans une revue hal-03832679v1
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Dual Blockade of Misfolded Alpha-Sarcoglycan Degradation by Bortezomib and Givinostat Combination

Lucile Hoch , Nathalie Bourg , Fanny Degrugillier , Céline Bruge , Manon Benabides et al.
Frontiers in Pharmacology, 2022, 13, ⟨10.3389/fphar.2022.856804⟩
Article dans une revue hal-03874719v1
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Generation of a heterozygous SCN5A knockout human induced pluripotent stem cell line by CRISPR/Cas9 edition

Marie Gizon , Laëtitia Duboscq-Bidot , Lina El Kassar , Pierre Bobin , Flavie Ader et al.
Stem Cell Research, 2022, 60, pp.102680. ⟨10.1016/j.scr.2022.102680⟩
Article dans une revue hal-03549731v1
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Myotonic dystrophy RNA toxicity alters morphology, adhesion and migration of mouse and human astrocytes

Diana Dincã , Louison Lallemant , Anchel González-Barriga , Noémie Cresto , Sandra Braz et al.
Nature Communications, 2022, 13 (1), pp.3841. ⟨10.1038/s41467-022-31594-9⟩
Article dans une revue hal-03715682v1
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CRISPR gene editing in pluripotent stem cells reveals the function of MBNL proteins during human in vitro myogenesis

Antoine Mérien , Julie Tahraoui-Bories , Michel Cailleret , Jean-Baptiste Dupont , Céline Leteur et al.
Human Molecular Genetics, 2022, 31 (1), pp.41-56. ⟨10.1093/hmg/ddab218⟩
Article dans une revue hal-03830948v1
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Skeletal Muscle Cells Derived from Induced Pluripotent Stem Cells: A Platform for Limb Girdle Muscular Dystrophies

Celine Bruge , Marine Geoffroy , Manon Benabides , Emilie Pellier , Evelyne Gicquel et al.
Biomedicines, 2022, 10 (6), pp.1428. ⟨10.3390/biomedicines10061428⟩
Article dans une revue hal-03858917v1
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Human iPSC-derived neurons reveal early developmental alteration of neurite outgrowth in the late-occurring neurodegenerative Wolfram syndrome

Sandra Pourtoy-Brasselet , Axel Sciauvaud , Maria-Gabriela Boza-Moran , Michel Cailleret , Margot Jarrige et al.
American Journal of Human Genetics, 2021, 108 (11), pp.2171-2185. ⟨10.1016/j.ajhg.2021.10.001⟩
Article dans une revue hal-03409417v1

Modulation of alternative splicing during early infection of human primary B lymphocytes with Epstein-Barr virus (EBV): a novel function for the viral EBNA-LP protein

Evelyne Manet , Hélène Polvèche , Fabrice Mure , Paulina Mrozek-Gorska , Florian Roisné-Hamelin et al.
Nucleic Acids Research, 2021, ⟨10.1093/nar/gkab787⟩
Article dans une revue hal-03357852v1

Identification of antiviral molecules against West-Nile virus by an approach combining cell imaging and equine neural cells derived from induced-pluripotent stem cells

Marielle Cochet-Bernoin , François Piumi , Kamila Gorna , Gaëlle Gonzalez , Anne Danckaert et al.
Journées Scientifiques et Doctorales de l'Anses (JSDA) 2021, Sep 2021, MAISONS-ALFORT, France
Poster de conférence hal-03355332v1
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Des embryons chimères et des pseudo-embryons comme alternatives pour la recherche sur l’embryon humain

Pierre Savatier , Laurent David , John de Vos , Frank Yates , Shahragim Tajbakhsh et al.
médecine/sciences, 2021, 37 (8-9), pp.799-801. ⟨10.1051/medsci/2021124⟩
Article dans une revue hal-03337388v1
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Integrative Cell Type-Specific Multi-Omics Approaches Reveal Impaired Programs of Glial Cell Differentiation in Mouse Culture Models of DM1

Anchel González-Barriga , Louison Lallemant , Diana M Dincã , Sandra O Braz , Hélène Polvèche et al.
Frontiers in Cellular Neuroscience, 2021, 15, pp.662035. ⟨10.3389/fncel.2021.662035⟩
Article dans une revue hal-03235993v1
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AAV2/9-mediated silencing of PMP22 prevents the development of pathological features in a rat model of Charcot-Marie-Tooth disease 1 A

Benoit Gautier , Helene Hajjar , Sylvia Soares , Jade Berthelot , Marie Deck et al.
Nature Communications, 2021, 12 (1), pp.2356. ⟨10.1038/s41467-021-22593-3⟩
Article dans une revue hal-03228637v1

Dynamic extrinsic pacing of the HOX clock in human axial progenitors controls motor neuron subtype specification

Vincent Mouilleau , Célia Vaslin , Rémi Robert , Simona Gribaudo , Nour Nicolas et al.
Development (Cambridge, England), 2021, 148 (6), ⟨10.1242/dev.194514⟩
Article dans une revue hal-03550019v1
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Myogenesis modelled by human pluripotent stem cells: a multi‐omic study of Duchenne myopathy early onset

Virginie Mournetas , Emmanuelle Massouridès , Jean-Baptiste Dupont , Etienne Kornobis , Hélène Polvèche et al.
Journal of Cachexia, Sarcopenia and Muscle, 2021, 12 (1), pp.209-232. ⟨10.1002/jcsm.12665⟩
Article dans une revue pasteur-03693397v1
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Les exosomes, des messagers intercellulaires naturels aux mécanismes polyvalents pour le traitement des myopathies?

Alexandra Bayer Wildberger , Judith Lorant , Jean-Thomas Vilquin
Les Cahiers de Myologie, A paraître, 37 (1), pp.44-45
Article dans une revue hal-03440216v1
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Deciphering DSC2 arrhythmogenic cardiomyopathy electrical instability: From ion channels to ECG and tailored drug therapy

Adrien Moreau , Jean‐baptiste Reisqs , Helene Delanoe‐ayari , Marion Pierre , Alexandre Janin et al.
Clinical and Translational Medicine, 2021, 11 (3), pp.e319. ⟨10.1002/ctm2.319⟩
Article dans une revue hal-03158834v1
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Generation of a human induced pluripotent stem cell line (iPSC) from peripheral blood mononuclear cells of a patient with a myasthenic syndrome due to mutation in COLQ

Susie Barbeau , Romain Desprat , Bruno Eymard , Cécile Martinat , Jean-Marc Lemaitre et al.
Stem Cell Research, 2020, 49, pp.102106. ⟨10.1016/j.scr.2020.102106⟩
Article dans une revue hal-03146055v1
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The HIF1α/JMY pathway promotes glioblastoma stem-like cell invasiveness after irradiation

Laurent R Gauthier , Mahasen Saati , Hayet Bensalah-Pigeon , Karim Ben M'Barek , Oscar Gitton-Quent et al.
Scientific Reports, 2020, 10 (1), pp.18742. ⟨10.1038/s41598-020-75300-5⟩
Article dans une revue hal-02989416v1
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Pathological modeling of TBEV infection reveals differential innate immune responses in human neurons and astrocytes that correlate with their susceptibility to infection

Mazigh Fares , Marielle Cochet-Bernoin , Gaëlle Gonzalez , Claudia Montero-Menei , Odile Blanchet et al.
Journal of Neuroinflammation, 2020, 17 (1), pp.76. ⟨10.1186/s12974-020-01756-x⟩
Article dans une revue inserm-02914090v1
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Human pluripotent stem cells: A toolbox to understand and treat retinal degeneration

Lise Morizur , Elise Herardot , Christelle Monville , Karim Ben M'Barek
Molecular and Cellular Neuroscience, 2020, 107, pp.103523 -. ⟨10.1016/j.mcn.2020.103523⟩
Article dans une revue hal-03492526v1
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Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13

Patricia R Pitrez , Luís Estronca , Luís Miguel Monteiro , Guillem Colell , Helena Vazão et al.
Nature Communications, 2020, 11 (1), pp.4110. ⟨10.1038/s41467-020-17901-2⟩
Article dans une revue inserm-02962684v1
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Intragenic recruitment of NF-κB drives splicing modifications upon activation by the oncogene Tax of HTLV-1

Lamya Ben Ameur , Paul Marie , Morgan Thénoz , Guillaume Giraud , Emmanuel Combe et al.
Nature Communications, 2020, 11 (1), pp.3045. ⟨10.1038/s41467-020-16853-x⟩
Article dans une revue inserm-02877333v1