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Article Dans Une Revue Physical Chemistry Chemical Physics Année : 2022

Syn-cryptophanes: macrocyclic compounds with optimized characteristics for the design of 129 Xe NMR-based biosensors

Résumé

A new water-soluble xenon host system with great promise for the 129 Xe NMR-based biosensing approach is presented: the syn-cryptophane-222-hexacarboxylate. It compares favorably with its already known anti diastereomer, on the one hand, and with cucurbit[6]uril, on the other hand, in particular in terms of xenon binding constant and xenon in-out exchange, a key parameter for the efficiency of the most sensitive HyperCEST method.

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Matériaux
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cea-03807625 , version 1 (10-10-2022)

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Estelle Léonce, Thierry Brotin, Patrick Berthault. Syn-cryptophanes: macrocyclic compounds with optimized characteristics for the design of 129 Xe NMR-based biosensors. Physical Chemistry Chemical Physics, 2022, 24, pp.24793-24799. ⟨10.1039/D2CP03714A⟩. ⟨cea-03807625⟩
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