Novel 1,6-naphthyridin-2(1H)-ones as potential anticancer agents targeting Hsp90.
David Montoir
,
Sophie Barillé-Nion
,
Alain Tonnerre
,
Philippe Juin
,
Muriel Duflos
et al.
Journal articles
inserm-01334013v1
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HLA-E-Restricted Cross-Recognition of Allogeneic Endothelial Cells by CMV-Associated CD8 T Cells: A Potential Risk Factor following Transplantation
Mathilde Allard
,
Pierre Tonnerre
,
Steven Nedellec
,
Romain Oger
,
Alexis Morice
et al.
Journal articles
inserm-01726990v1
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Pathogenesis of Myeloproliferative Neoplasms: Role and Mechanisms of Chronic Inflammation
Sylvie Hermouet
,
Edith Bigot-Corbel
,
Betty Gardie
Journal articles
inserm-01402440v1
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Extracellular vesicle-transported Semaphorin3A promotes vascular permeability in glioblastoma
L Treps
,
S Edmond
,
E Harford-Wright
,
Em Galan-Moya
,
Anne Schmitt
et al.
Journal articles
inserm-01406334v1
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The paracaspase MALT1 cleaves the LUBAC subunit HOIL1 during antigen receptor signaling
Tiphaine Douanne
,
Julie Gavard
,
Nicolas Bidère
Journal articles
inserm-01311283v1
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Baseline Peripheral Blood Biomarkers Associated with Clinical Outcome of Advanced Melanoma Patients Treated with Ipilimumab
Alexander A Martens
,
Kilian K Wistuba-Hamprecht
,
Marnix Geukes Foppen
,
Jianda Yuan
,
Michael A Postow
et al.
Journal articles
inserm-01409624v1
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Proportions of blood-borne Vd1þ and Vd2þ T-cells are associated with overall survival of melanoma patients treated with ipilimumab
Kilian U Wistuba-Hamprecht
,
Alexander U Martens
,
Karin U Haehnel
,
Marnix A Geukes Foppen
,
Jianda U Yuan
et al.
Journal articles
inserm-01408787v1
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IL-34 and M-CSF form a novel heteromeric cytokine and regulate the M-CSF receptor activation and localization
Aude Segaliny
,
Régis Brion
,
Bénédicte Brulin
,
Mike Maillasson
,
Céline Charrier
et al.
Journal articles
inserm-01644778v1
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OLIGOPELVIS – GETUG P07: a multicentre phase II trial of combined salvage radiotherapy and hormone therapy in oligometastatic pelvic node relapses of prostate cancer
Stéphane Supiot
,
Emmanuel Rio
,
Valérie Pacteau
,
Marie-Hélène Mauboussin
,
Loïc Campion
et al.
Journal articles
inserm-01817526v1
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Impact of stem cell graft on early viral infections and immune reconstitution after allogeneic transplantation in adults
Marina Illiaquer
,
Berthe-Marie Imbert-Marcille
,
Thierry Guillaume
,
Lucie Planche
,
Marie Rimbert
et al.
Journal articles
inserm-01819344v1
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Age-related clinical and biological features of PTEN abnormalities in T-cell acute lymphoblastic leukaemia
M Tesio
,
A. Trinquand
,
P Ballerini
,
G Hypolite
,
L. Lhermitte
et al.
Journal articles
inserm-01819388v1
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Targeting IRAK1 in T-Cell acute lymphoblastic leukemia
Charles Dussiau
,
Amélie Trinquand
,
Ludovic Lhermitte
,
Mehdi Latiri
,
Mathieu Simonin
et al.
Oncotarget , 2015, 6 (22), pp.18956-65
Journal articles
inserm-01820237v1
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Gene-expression molecular subtyping of triple-negative breast cancer tumours: importance of immune response
Pascal Jézéquel
,
Delphine Loussouarn
,
Catherine Guérin-Charbonnel
,
Loïc Campion
,
Antoine Vanier
et al.
Journal articles
inserm-01820311v1
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Desert Hedgehog/Patch2 Axis Contributes to Vascular Permeability and Angiogenesis in Glioblastoma
Sandy Azzi
,
Lucas Treps
,
Héloïse M. Leclair
,
Hai-Mi Ngo
,
Elizabeth Harford-Wright
et al.
Journal articles
inserm-01247505v1
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How I treat extramedullary myeloma
Cyrille Touzeau
,
Philippe Moreau
Journal articles
inserm-01411096v1
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A gene expression and pre-mRNA splicing signature that marks the adenoma-adenocarcinoma progression in colorectal cancer.
Marine Pesson
,
Alain Volant
,
Arnaud Uguen
,
Kilian Trillet
,
Pierre de La Grange
et al.
Journal articles
hal-00976068v1
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Small lymphocytic lymphoma, marginal zone B-cell lymphoma, and mantle cell lymphoma exhibit distinct gene-expression profiles allowing molecular diagnosis
C Thieblemont
,
V Nasser
,
P Felman
,
K Leroy
,
S Gazzo
et al.
Journal articles
hal-01612152v1
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In vivo 212Pb/212Bi generator using indium-DTPA-tagged liposomes
A. Le Du
,
M. Mougin-Degraef
,
Eliot Patrick Botosoa
,
Aurore Rauscher
,
Alain Faivre-Chauvet
et al.
Journal articles
in2p3-00617427v1
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Nouvelles stratégies de radio-nanomédecines pour le ciblage de cellules souches dans le glioblastome
D Séhédic
,
François Hindré
,
Jacques Barbet
,
Jean-Pierre Benoît
,
F. Davodeau
et al.
Journée scientifique IFR 132 , 2011, Angers, France. 2011
Conference poster
hal-03180623v1
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Systemic and immune manifestations in myelodysplasia: a multicenter retrospective study
A. de Hollanda
,
Alain Beucher
,
Daniel Henrion
,
Alaa Ghali
,
Christian Lavigne
et al.
Arthritis Care & Research = Arthritis Care and Research , 2011, 63 (8), pp.1188 - 94.
⟨10.1002/acr.20504⟩
Journal articles
hal-03408516v1
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Exogenous human herpesvirus 6 reinfection after tumor-infiltrating T-lymphocyte therapy
Anastasiia Filippova
,
Julie Charles
,
Olivier Epaulard
,
Raphaële Germi
,
Virginie Persoons
et al.
Journal articles
hal-02059880v1
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Synthesis and biological studies of new piperidino-1,2,3-triazole hybrids with 3-aryl isoxazole side chains
Appala Venkata Ramana Murthy
,
Vennu Narendar
,
Nangunoori Sampath Kumar
,
Pasula Aparna
,
Anagani Kanaka Durga Bhavani
et al.
Journal articles
hal-03414697v1
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CpG-Paclitaxel-loaded LNC for the treatment of glioblastoma
Giovanna Lollo
,
Marie Vincent
,
Gabriella Ullia
,
Laurent Lemaire
,
Dominique Couez
et al.
2nd International Meeting on Translational Nanomedicines , 2014, Angers, France. 2014
Conference poster
hal-03173120v1
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Targeting CD8 T-Cell Metabolism in Transplantation
Michelle Yap
,
Sophie Brouard
,
Claire Pecqueur
,
Nicolas Degauque
Journal articles
inserm-02147167v1
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Mycobacterial phosphatidyl inositol mannosides negatively regulate host toll-like receptor 4, MYD88-dependent proinflammatory cytokines and trif-dependent co-stimulatory molecules expression.
Emilie Doz
,
Stéphanie Rose
,
Nathalie Court
,
Sophie Front
,
Virginie Vasseur
et al.
Journal articles
hal-00404964v1
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Biological rational for sequential targeting of Bruton tyrosine kinase and Bcl-2 to overcome CD40-induced ABT-199 resistance in mantle cell lymphoma
David Chiron
,
Christelle Dousset
,
Carole Brosseau
,
Cyrille Touzeau
,
Sophie Maïga
et al.
Journal articles
inserm-02534385v1
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Definition and Characterization of an Inhibitor for Interleukin-31
Emilie Venereau
,
Caroline Diveu
,
Linda Grimaud
,
Elisa Ravon
,
Josy Froger
et al.
Journal articles
hal-01680095v1
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Les déchets solides hospitaliers : quantification, analyses bactériologiques. Cas de l'hôpital Ibn Sina - Rabat - Maroc
Meriem Bahri
,
Rachid Belkhadir
,
Yahya Koulali
,
Larbi Idrissi
,
Abdelhamid Khadri
et al.
Journal articles
hal-03173737v1
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Brentuximab vedotin in refractory or relapsed peripheral T-cell lymphomas: the French named patient program experience in 56 patients
Mathilde Lamarque
,
Céline Bossard
,
Adrien Contejean
,
Pauline Brice
,
Marie Parrens
et al.
Journal articles
inserm-01419525v1
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3,4-Dideoxy-3,3,4,4-tetrafluoro- and 4-OH epimeric 3-deoxy-3,3-difluoro-α-GalCer analogues: Synthesis and biological evaluation on human iNKT cells stimulation
Samuel Golten
,
Allan Patinec
,
Katy Akoumany
,
Jézabel Rocher
,
Jérôme Graton
et al.
Journal articles
hal-03086847v1
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Unique Functional Status of Natural Killer Cells in Metastatic Stage IV Melanoma Patients and Its Modulation by Chemotherapy
Giulia Fregni
,
Aurélie Perier
,
Gianfranco Pittari
,
Simon Jacobelli
,
Xavier Sastre
et al.
Journal articles
inserm-03349277v1
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Double Positive CD4CD8 αβ T Cells: A New Tumor-Reactive Population in Human Melanomas
Juliette Desfrançois
,
Agnès Moreau-Aubry
,
Virginie Vignard
,
Yann Godet
,
Amir U Khammari
et al.
Journal articles
inserm-03349309v1
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Irinotecan treatment and senescence failure promote the emergence of more transformed and invasive cells that depend on anti-apoptotic Mcl-1.
Barbara Jonchère
,
Alexandra Vétillard
,
Bertrand Toutain
,
David Lam
,
Anne-Charlotte Bernard
et al.
Journal articles
hal-01396743v1
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Septic Shock Sera Containing Circulating Histones Induce Dendritic Cell–Regulated Necrosis in Fatal Septic Shock Patients
Loïc Raffray
,
Isabelle Douchet
,
Jean-François Augusto
,
Jihad Youssef
,
Cecile Contin-Bordes
et al.
Journal articles
hal-01392235v1
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Sequencing of the hypoxia pathway genes in patients with congenital erythrocytoses by next generation sequencing
F. Girodon
,
F. Pacault
,
M. Airaud
,
C. Garrec
,
S. Corbineau
et al.
22nd Congress of the European Hematology Association , Jun 2017, Madrid, Spain. pp.P712
Conference papers
hal-01633522v1
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NMR investigation of targeted therapy effects on the host metabolism for HER-2 positive breast cancer
Elodie Jobard
,
Thomas Bachelot
,
Mario Campone
,
Olivier Trédan
,
Bénédicte Elena-Herrmann
et al.
10èmes Journées Scientifiques du Réseau Francophone de Métabolomique et Fluxomique , RFMF - Réseau Francophone de Métabolomique et Fluxomique May 2016, Montpellier, France
Conference papers
hal-01575749v1
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Findings in Patients From Benin With Osteomyelitis and Polymerase Chain Reaction–Confirmed Mycobacterium ulcerans Infection
Virginie Pommelet
,
Quentin Vincent
,
Marie-Françoise Ardant
,
Ambroise Adeye
,
Anca Tanase
et al.
Journal articles
hal-01390735v1
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Olfactomedin-4 is a candidate biomarker of solid gastric, colorectal, pancreatic, head and neck, and prostate cancers
Catherine Guette
,
Isabelle Valo
,
Alexandra Vétillard
,
Olivier Coqueret
Journal articles
istex
hal-01392237v1
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A Ring-D-Seco-Tetranortriterpenoid from Seeds of Carapa procera Active against Breast Cancer Cell Lines.
Mbaye Diaw Dioum
,
Matar Seck
,
Virginie Silvestre
,
Aurélien Planchat
,
Denis Loquet
et al.
Journal articles
inserm-01333918v1
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ERK-regulated differential expression of the Mitf 6a/b splicing isoforms in melanoma.
Aline Primot
,
Ariane Mogha
,
Sébastien Corre
,
Karen Roberts
,
Julien Debbache
et al.
Journal articles
inserm-00435177v1
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[Quantitative assessment of medical students' clinical practical learning in department of obstetrics and gynecology of Brest Hospital University].
Matthieu Muller
,
X. Monfort
,
Pierre-François Dupré
,
Paul Amouroux
,
R. Tétefort
et al.
Journal articles
hal-00931262v1
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Intensification thérapeutique dans les cancers colorectaux par des études pharmacogénétiques et pharmacogénomiques
Olivier Capitain
Médicaments. Université d'Angers, 2010. Français.
⟨NNT : ⟩
Theses
tel-00536079v1
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NPY promotes chemokinesis and neurogenesis in the rat subventricular zone.
Nathalie Thiriet
,
Fabienne Agasse
,
Camille Nicoleau
,
Christelle Guégan
,
François M. Vallette
et al.
Journal articles
hal-00582387v1
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Protein crystallization promotes type 2 immunity and is reversible by antibody treatment
Emma Persson
,
Kenneth Verstraete
,
Ines Heyndrickx
,
Elien Gevaert
,
Helena Aegerter
et al.
Journal articles
hal-02542110v1
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Severe Viral Hepatitis in a Patient with Chronic Lymphocytic Leukemia (CLL) Complicated with Autoimmune Haemolytic Anemia (AIAH), Treated with Steroids
Corentin Orvain
,
Alexandra Ducancelle
,
Caroline Eymerit-Morin
,
Marie-Christine Rousselet
,
Frederic Oberti
et al.
Journal articles
inserm-03402266v1
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Increased cerebral blood flow velocities assessed by transcranial Doppler examination is associated with complement activation after cardiopulmonary bypass
Christophe Baufreton
,
Frédéric Pinaud
,
Jean-Jacques Corbeau
,
Alain Chevailler
,
D. Jolivot
et al.
Journal articles
hal-03405225v1
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In vitro protection of vascular function from oxidative stress and inflammation by pulsatility in resistance arteries
Frédéric Pinaud
,
Laurent Loufrani
,
Bertrand Toutain
,
Diane Lambert
,
Lionel Vandekerckhove
et al.
Journal articles
hal-03405258v1
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Defining and targeting high-risk populations in Buruli ulcer–Authors' reply
Quentin Vincent
,
Marie-Françoise Ardant
,
Laurent Marsollier
,
Annick Chauty
,
Alexandre Alcaïs
et al.
The Lancet global health , 2014, 2 (11), pp.e630
Journal articles
hal-03389733v1
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gamma-secretase inhibition promotes cell death, Noxa upregulation and sensitization to BH3 mimetic ABT-737 in human breast cancer cells.
Céline Séveno
,
Delphine Loussouarn
,
Sophie Bréchet
,
Mario Campone
,
Philippe Juin
et al.
Journal articles
inserm-00713823v1
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Prospective comparison of FDG PET/CT and diffusion-weighted MRI for para-aortic metastases detection in cancer of the uterine cervix.
A. Carlier
,
T. Eugène
,
A. Faivre-Chauvet
,
F. Kraeber-Bodéré
,
R. Lebtahi
et al.
SNM 60th Annual Meeting , 2013, Vancouver, Canada
Conference papers
hal-00945039v1
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Glycosylation-related gene expression is linked to differentiation status in glioblastomas undifferentiated cells.
Mathilde Cheray
,
Daniel Petit
,
Lionel Forestier
,
Lucie Karayan-Tapon
,
Abderrahman Maftah
et al.
Journal articles
hal-00873130v1
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The Natural History of Clinical Operational Tolerance After Kidney Transplantation Through Twenty-Seven Cases
S. Brouard
,
A. Pallier
,
Karine Renaudin
,
Y. Foucher
,
R. Danger
et al.
Journal articles
hal-03388058v1
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Is there an interest to use deuteron beams to produce nonconventional radionuclides?
C. Alliot
,
N. Audouin
,
J. Barbet
,
A.C. Bonraisin
,
V. Bosse
et al.
Conference papers
hal-02930789v1
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Coupe le cordon, vole de tes propres ailes !
Erwan Mortier
,
Fella Tamzalit
,
Yannick Jacques
,
Sébastien Morisseau
Journal articles
inserm-02437321v1
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Curcumin induces cell death of the main molecular myeloma subtypes, particularly the poor prognosis subgroups
Patricia Gomez-Bougie
,
Maxime Halliez
,
Sophie Maïga
,
Catherine Godon
,
Charlotte Kervoëlen
et al.
Journal articles
inserm-02534388v1
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Radiation-induced PGE 2 sustains human glioma cell growth and survival through EGF signaling
Emeline Brocard
,
Kristell Oizel
,
Lisenn Lalier
,
Claire Pecqueur
,
François Paris
et al.
Journal articles
inserm-02914000v1
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Peripheral CD8 effector-memory type 1 T-cells correlate with outcome in ipilimumab-treated stage IV melanoma patients
Kilian Wistuba-Hamprecht
,
Alexander Martens
,
Florian Heubach
,
Emanuela Romano
,
Marnix Geukes Foppen
et al.
Journal articles
inserm-01808248v1
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Ipilimumab 10 mg/kg versus ipilimumab 3 mg/kg in patients with unresectable or metastatic melanoma: a randomised, double-blind, multicentre, phase 3 trial
Paolo A Ascierto
,
Michele Del Vecchio
,
Caroline Robert
,
Andrzej Mackiewicz
,
Vanna Chiarion-Sileni
et al.
Journal articles
inserm-01807340v1
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Predictive value of intratumoral signaling and immune infiltrate in primary breast cancer (PBC) for response to preoperative trastuzumab (T) vs trastuzumab + everolimus (T+E) in patients (pts) with early breast cancer (BC) : Unicancer RADHER trial results
Mario Campone
,
Isabelle Treilleux
,
Julia Salleron
,
Monica Arnedos
,
Qing Wang
et al.
ASCO 2016 annual meeting , Jun 2016, Chicago, IL, United States. pp.abstr 606
Conference papers
hal-01320584v1
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Detection of RHDV strains in the Iberian hare (Lepus granatensis): earliest evidence of rabbit lagovirus cross-species infection
Ana M Lopes
,
Sara Marques
,
Eliane Silva
,
Maria J Magalhães
,
Ana Pinheiro
et al.
Journal articles
hal-01290590v1
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Sustained fecal-oral human-to-human transmission following a zoonotic event
Miranda M de Graaf
,
Relja Beck
,
Simone S Caccio
,
Birgitta La Duim
,
Pieter S Fraaij
et al.
Journal articles
inserm-01445250v1
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UCP2 induces metabolic reprogramming to inhibit proliferation of cancer cells
Esteves Pauline
,
Claire Pecqueur
,
Alves-Guerra Marie-Clotilde
Journal articles
inserm-01207304v1
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Cross-Reactive Donor-Specific CD8+ Tregs Efficiently Prevent Transplant Rejection
Elodie Picarda
,
Séverine Bézie
,
Lorena Usero
,
Jason Ossart
,
Marine Besnard
et al.
Journal articles
inserm-02449068v1
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Low non-relapse mortality and long-term preserved quality of life in older patients undergoing matched related donor allogeneic stem cell transplantation: a prospective multicenter phase II trial
Didier Blaise
,
Raynier Devillier
,
Anne-Gaelle Lecoroller-Sorriano
,
Jean-Marie Boher
,
Agnès Boyer-Chammard
et al.
Journal articles
hal-02167058v1
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Comparison of Spheroids Formed by Rat Glioma Stem Cells and Neural Stem Cells Reveals Differences in Glucose Metabolism and Promising Therapeutic Applications
Marie Morfouace
,
Lisenn Lalier
,
Muriel Bahut
,
Virginie Bonnamain
,
Philippe Naveilhan
et al.
Journal articles
inserm-03369867v1
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Overexpression of Meloe Gene in Melanomas Is Controlled Both by Specific Transcription Factors and Hypomethylation
Mathilde Bobinet
,
Virginie Vignard
,
Laeticia Florenceau
,
François Lang
,
Nathalie Labarrière
et al.
Journal articles
inserm-02481919v1
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Matrix metalloproteinase-2 Conditions Human Dendritic Cells to Prime Inflammatory T(H)2 Cells via an IL-12- And OX40L-dependent Pathway
Emmanuelle Godefroy
,
Olivier Manches
,
Brigitte Dréno
,
Tsivia Hochman
,
Linda Rolnitzky
et al.
Journal articles
inserm-02483749v1
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Implication de la Caspase-3 dans la différenciation des cellules souches adultes ?
Erika Hue
,
Gwenola Bougras-Cartron
,
Lisa Oliver
,
Francois Vallette
Forum des Doctorants , 2008, Nantes, France
Conference poster
hal-03454687v1
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IgM peak independently predicts treatment-free survival in chronic lymphocytic leukemia and correlates with accumulation of adverse oncogenetic events
D Rizzo
,
J Chauzeix
,
F. Trimoreau
,
J B Woillard
,
F Genevieve
et al.
Journal articles
inserm-02517072v1
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