Targeting Metabolism to Induce Cell Death in Cancer Cells and Cancer Stem Cells - Archive ouverte HAL Access content directly
Journal Articles International Journal of Biochemistry and Cell Biology Year : 2013

Targeting Metabolism to Induce Cell Death in Cancer Cells and Cancer Stem Cells

(1) , (1, 2) , (1) , (1, 3) , (1, 3)
1
2
3

Abstract

Abnormal metabolism and the evasion of apoptosis are considered hallmarks of cancers. Accumulating evidence shows that cancer stem cells are key drivers of tumor formation, progression, and recurrence. A successful therapy must therefore eliminate these cells known to be highly resistant to apoptosis. In this paper, we describe the metabolic changes as well as the mechanisms of resistance to apoptosis occurring in cancer cells and cancer stem cells, underlying the connection between these two processes.
Fichier principal
Vignette du fichier
IJCB2013-805975.pdf (1.41 Mo) Télécharger le fichier
Origin : Publication funded by an institution
Loading...

Dates and versions

inserm-02447021 , version 1 (21-01-2020)

Identifiers

Cite

Claire Pecqueur, Lisa Oliver, Kristell Oizel, Lisenn Lalier, François M Vallette. Targeting Metabolism to Induce Cell Death in Cancer Cells and Cancer Stem Cells. International Journal of Biochemistry and Cell Biology, 2013, 2013, pp.805975. ⟨10.1155/2013/805975⟩. ⟨inserm-02447021⟩
46 View
50 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More