Mechanisms of action of antithymocyte globulin: old dogs with new tricks! - Centre de recherche en cancérologie Nantes-Angers Unité Mixte de Recherche 892 Inserm - 6299 CNRS Access content directly
Journal Articles Leukemia & lymphoma Year : 2008

Mechanisms of action of antithymocyte globulin: old dogs with new tricks!

Abstract

Understanding the mechanisms underlying immunological tolerance is the key to successful transplantation. Recent findings demonstrate that polyclonal antibodies such as the antithymocyte globulins preparations can provide wide spectrum immunomodulation, suggesting that their use in the immunosuppression therapeutic armamentarium may help in reducing the incidence of organ rejection and improving patients' outcome after hematopoietic stem cell transplantation.

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Immunology
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Dates and versions

inserm-00479757 , version 1 (02-05-2010)

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Mohamad Mohty, Beatrice Gaugler. Mechanisms of action of antithymocyte globulin: old dogs with new tricks!. Leukemia & lymphoma, 2008, 49 (9), pp.1664-7. ⟨10.1080/10428190802163321⟩. ⟨inserm-00479757⟩
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