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Article Dans Une Revue Current Opinion in Virology Année : 2017

Human transmission of Ebola virus

Résumé

Ever since the first recognised outbreak of Ebolavirus in 1976, retrospective epidemiological analyses and extensive studies with animal models have given us insight into the nature of the pathology and transmission mechanisms of this virus. In this review focusing on Ebolavirus, we present an outline of our current understanding of filovirus human-to-human transmission and of our knowledge concerning the molecular basis of viral transmission and potential for adaptation, with particular focus on what we have learnt from the 2014 outbreak in West Africa. We identify knowledge gaps relating to transmission and pathogenicity mechanisms, molecular adaptation and filovirus ecology.
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Dates et versions

hal-01911336 , version 1 (02-11-2018)

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Citer

Philip Lawrence, Nicolas Danet, Olivier Reynard, Valentina Volchkova, Viktor Volchkov. Human transmission of Ebola virus. Current Opinion in Virology, 2017, 22, pp.51-58. ⟨10.1016/j.coviro.2016.11.013⟩. ⟨hal-01911336⟩
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